Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73092.1KEGG: mfe:Mefer_0784 hypothetical protein. (258 aa)    
Predicted Functional Partners:
lysS
KEGG: mfe:Mefer_0785 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.676
ACX73093.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mja:MJ0537 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
       0.643
ACX71989.1
TIGRFAM: S-layer protein; PFAM: S-layer family protein; KEGG: mfe:Mefer_0912 S-layer protein.
       0.594
ACX72483.1
PFAM: Radical SAM domain protein; KEGG: mja:MJ0808 pyruvate-formate-lyase-activating enzyme (act).
       0.594
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.594
ACX72173.1
SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0043 hypothetical protein.
       0.573
ACX72815.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ1595 hypothetical protein.
       0.568
ACX73076.1
PFAM: Cl- channel voltage-gated family protein; KEGG: mja:MJ0305 hypothetical protein.
       0.459
ACX73094.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: mfe:Mefer_0782 pyruvate/ketoisovalerate oxidoreductase, gamma subunit.
       0.435
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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