Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73113.1PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: mja:MJ1480 hypothetical protein. (423 aa)    
Predicted Functional Partners:
ACX73112.1
PFAM: Protein of unknown function DUF2100; KEGG: mja:MJ1481 hypothetical protein.
  
    0.922
pgk2
PFAM: ATP-cone domain protein; KEGG: mja:MJ1482 2-phosphoglycerate kinase.
  
    0.884
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
      
 0.630
ACX72715.1
PFAM: amino acid-binding ACT domain protein; KEGG: mja:MJ1458 hypothetical protein.
  
     0.534
ACX73114.1
PFAM: protein of unknown function UPF0153; KEGG: mja:MJ1479.1 hypothetical protein.
       0.495
ACX73403.1
PFAM: SufBD protein; KEGG: mja:MJ0034 hypothetical protein.
   
    0.429
ACX72107.1
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mfe:Mefer_0143 agmatinase; Belongs to the arginase family.
     
 0.428
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (38%) [HD]