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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ACX73139.1PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mja:MJ0033 succinate dehydrogenase flavoprotein subunit. (531 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.997
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.995
ACX73102.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; ferredoxin; KEGG: mja:MJ0092 succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
 
  
 0.981
ACX72646.1
KEGG: mfe:Mefer_0211 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
  
 
 0.976
ACX72377.1
KEGG: mja:MJ1294 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
  
 
 0.975
ACX73552.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1302 ferredoxin.
  
 
 0.960
ACX72389.1
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
   
 0.946
ACX72226.1
PFAM: Lactate/malate dehydrogenase; KEGG: mfe:Mefer_0722 malate dehydrogenase (NADP(+)); Belongs to the LDH/MDH superfamily.
 
 
 0.932
ACX73152.1
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: mja:MJ0999 thermosome (ths).
 
 
 0.837
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.834
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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