Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73187.1PFAM: protein of unknown function DUF58; KEGG: pfu:PF0417 hypothetical protein. (458 aa)    
Predicted Functional Partners:
ACX73184.1
PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: pfu:PF0420 hypothetical protein.
 
     0.960
ACX73186.1
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: pab:PAB1276 methanol dehydrogenase regulatory protein.
 
  
 0.960
ACX73185.1
KEGG: pho:PH0328 hypothetical protein.
       0.861
ACX73188.1
KEGG: bhy:BHWA1_00261 hypothetical protein.
       0.773
ACX73048.1
PFAM: ATPase associated with various cellular activities AAA_5; KEGG: mja:MJ0079 regulatory protein, putative (MoxR).
 
  
 0.580
ACX71952.1
PFAM: ATPase associated with various cellular activities AAA_5; KEGG: mja:MJ0812 hypothetical protein.
 
  
 0.540
ACX72190.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: mja:MJ0793 hypothetical protein.
 
  
 0.515
ACX72861.1
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; Tetratricopeptide repeat; KEGG: tga:TGAM_0974 serine/threonine protein kinase.
  
  
 0.445
rad50
SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
  
  
 0.429
ACX73183.1
PFAM: Protein of unknown function DUF22; KEGG: mja:MJ0614 hypothetical protein.
       0.414
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.