STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73224.1PFAM: PilT protein domain protein; KH type 2 domain protein; K Homology, type 1, subgroup; SMART: Nucleotide binding protein PINc; Hedgehog/intein hint domain protein; KH domain protein; KEGG: mja:MJ1533 ATPase. (1243 aa)    
Predicted Functional Partners:
ACX71972.1
PFAM: Peptidase A24B, FlaK domain protein; peptidase A24A prepilin type IV; KEGG: mja:MJ0902 hypothetical protein.
 
   
 0.748
ACX71971.1
PFAM: Type II secretion system F domain; KEGG: mja:MJ0901 flagellar assembly protein J.
  
   
 0.635
ACX71994.1
PFAM: band 7 protein; SMART: band 7 protein; KEGG: mfe:Mefer_0918 band 7 protein.
      
 0.630
ACX71969.1
SMART: AAA ATPase; KEGG: mja:MJ0899 flagellar accessory protein FlaH.
  
   
 0.622
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
   
 0.611
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.594
hisS
KEGG: mfe:Mefer_1228 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.586
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
     0.583
ACX71970.1
PFAM: type II secretion system protein E; KEGG: mja:MJ0900 type II secretion system protein.
 
   
 0.551
ACX71955.1
KEGG: mja:MJ0885 DNA polymerase B1; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein.
  
   
 0.550
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.