STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACX73286.1PFAM: protein of unknown function DUF129; KEGG: mja:MJ1361 hypothetical protein. (290 aa)    
Predicted Functional Partners:
cofE
F420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
  
  
  0.816
ACX72776.1
PFAM: PhoU family protein; KEGG: mfe:Mefer_1330 phosphate uptake regulator, PhoU.
  
     0.564
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.556
ACX73503.1
TIGRFAM: pyridoxal phosphate enzyme; KEGG: mja:MJ0158 selenocystein synthase (SelA).
  
     0.533
ACX72992.1
PFAM: glucose-methanol-choline oxidoreductase; KEGG: mja:MJ1450 hypothetical protein.
  
     0.527
ACX72165.1
PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: mja:MJ0138 cobyrinic acid a,c-diamide synthase.
  
    0.507
ACX72110.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: mja:MJ1525 putative transmembrane oligosaccharyl transferase.
  
     0.454
ACX72786.1
PFAM: regulatory protein LysR; KEGG: mfe:Mefer_0298 transcriptional regulator, LysR family.
  
    0.453
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
     0.449
cofD
LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
     0.447
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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