Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73294.1TIGRFAM: methanogenesis marker protein 1; PFAM: protein of unknown function DUF181; KEGG: mja:MJ1094 hypothetical protein. (385 aa)    
Predicted Functional Partners:
ACX72042.1
TIGRFAM: SagB-type dehydrogenase domain; PFAM: nitroreductase; KEGG: mfe:Mefer_0593 SagB-type dehydrogenase domain protein.
 
  
 0.878
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
       0.713
ACX72017.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
   
 0.639
ACX72394.1
TIGRFAM: methanogenesis marker protein 6; PFAM: conserved hypothetical protein; KEGG: mja:MJ0498 hypothetical protein.
 
     0.638
ACX73052.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
   
 0.635
ACX72015.1
TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C; KEGG: mja:MJ0844 methyl coenzyme M reductase I, operon protein C (McrC).
 
     0.630
ACX72689.1
TIGRFAM: methanogenesis marker protein 5; PFAM: conserved hypothetical protein; KEGG: mfe:Mefer_1315 methanogenesis marker protein 5.
 
     0.597
ACX73295.1
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mja:MJ1498 modification methylase, type II R/M system.
 
     0.590
ACX72013.1
KEGG: mja:MJ0842 methyl coenzyme M reductase I, subunit beta (McrB); TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
     0.587
ACX73104.1
TIGRFAM: methanogenesis marker protein 7; PFAM: Protein of unknown function UCP019164; KEGG: mja:MJ0094 methyl coenzyme M reductase II, operon protein C (MtrC).
 
     0.575
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.