Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73306.1TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mja:MJ0709 hypothetical protein. (460 aa)    
Predicted Functional Partners:
ACX73307.1
PFAM: putative RNA methylase; THUMP domain protein; DNA methylase N-4/N-6 domain protein; KEGG: mfe:Mefer_1079 putative RNA methylase.
  
    0.884
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.844
gap
KEGG: mfe:Mefer_0809 glyceraldehyde-3-phosphate dehydrogenase, type II; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase.
  
  
 0.803
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.722
rps6e
PFAM: Ribosomal protein S6e; KEGG: mja:MJ1260 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
   0.691
rpl40e
KEGG: mfe:Mefer_1082 hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
 
 
 
 0.689
rps17
Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.685
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
   
 
 0.683
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 
 0.668
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.667
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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