STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73350.1PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mfe:Mefer_1110 response regulator receiver protein. (124 aa)    
Predicted Functional Partners:
ACX72123.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: mfe:Mefer_0642 CheW protein.
  
 0.998
ACX72125.1
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; CheW domain protein; SMART: Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; KEGG: mfe:Mefer_0640 CheA signal transduction histidine kinase.
 
 
 0.998
ACX73283.1
PFAM: chemotaxis sensory transducer; Rhodanese domain protein; SMART: chemotaxis sensory transducer; Rhodanese domain protein; KEGG: mmp:MMP0413 hypothetical protein.
 
 0.988
ACX73351.1
PFAM: CheC domain protein; KEGG: mfe:Mefer_1109 CheC, inhibitor of MCP methylation.
 
 
 0.984
ACX73352.1
PFAM: CheC domain protein; KEGG: mfe:Mefer_1108 CheC, inhibitor of MCP methylation.
 
 
 0.982
ACX73348.1
PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: mfe:Mefer_1112 methyl-accepting chemotaxis sensory transducer.
 
 0.981
ACX72122.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: mfe:Mefer_0025 methyl-accepting chemotaxis sensory transducer.
 
 0.975
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.942
ACX73349.1
PFAM: Protein of unknown function DUF439; KEGG: mfe:Mefer_1111 protein of unknown function DUF439.
   
 
 0.902
ACX72383.1
KEGG: mfe:Mefer_1107 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
 
  
 0.894
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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