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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ACX73451.1PFAM: Protein of unknown function DUF137; KEGG: mja:MJ0209 hypothetical protein. (258 aa)    
Predicted Functional Partners:
ACX72228.1
GHMP kinase; KEGG: mfe:Mefer_0856 GHMP kinase.
 
  
 0.991
ACX71984.1
KEGG: mja:MJ0913 pantothenate metabolism flavoprotein (dfp); TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
 
  
 0.974
mfnA
Pyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.929
ACX73450.1
TIGRFAM: archaeoflavoprotein, MJ0208 family; PFAM: flavoprotein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0208 4Fe-4S iron-sulfur protein.
       0.763
ACX72280.1
KEGG: mja:MJ1399 hypothetical protein; Belongs to the UPF0200 family.
 
     0.735
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
  
    0.633
ACX72744.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0550 protein of unknown function DUF54; Belongs to the UPF0201 family.
 
   
 0.624
ACX73336.1
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
       0.594
dadD
Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...]
       0.593
ACX72958.1
PFAM: NMD3 family protein; KEGG: mja:MJ1650 hypothetical protein.
 
     0.593
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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