Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73479.1TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: mja:MJ0200 hydrogenase expression/formation protein (HypC). (81 aa)    
Predicted Functional Partners:
ACX72244.1
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: mja:MJ0993 hydrogenase expression/formation protein (HypD).
 
 
 0.988
ACX72928.1
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: mja:MJ0676 hydrogenase expression/formation protein (HypE).
 
 
 0.964
ACX72050.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0442 hydrogenase expression/formation protein (HypB).
 
  
 0.949
ACX73408.1
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: mja:MJ0713 hydrogenase expression regulatory protein (HypF).
 
 
 0.897
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
  
 
 0.890
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.856
nac
alpha-NAC related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.573
ACX72718.1
PFAM: protein of unknown function DUF89; KEGG: mja:MJ0202 hypothetical protein.
 
     0.461
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A (MobA); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
       0.437
ACX72574.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mae:Maeo_0097 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.435
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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