Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73510.1PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mja:MJ0165 hypothetical protein. (261 aa)    
Predicted Functional Partners:
ACX71996.1
PFAM: PP-loop domain protein; KEGG: mja:MJ0830 hypothetical protein.
 
  
 0.977
ACX72602.1
PFAM: protein of unknown function DUF111; KEGG: mja:MJ1387 hypothetical protein; Belongs to the LarC family.
 
  
 0.955
dtdA
Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
       0.933
ACX73512.1
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: mja:MJ0167 molybdenum cofactor biosynthesis protein (MoaB).
       0.899
ACX73509.1
PFAM: Protein of unknown function DUF2226; KEGG: mja:MJ0164 hypothetical protein.
       0.843
ACX73508.1
PFAM: Roadblock/LC7 family protein; KEGG: mja:MJ0163 hypothetical protein.
  
    0.811
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.706
ACX73174.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: mja:MJ1569 cobalt transport protein CbiM.
  
    0.573
ACX73175.1
KEGG: mja:MJ1570 hypothetical protein.
  
    0.573
ACX73134.1
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
       0.432
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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