Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73513.1PFAM: Transcription factor CBF/NF-Y/histone domain protein; Histone core domain protein; TATA box binding protein associated factor (TAF); KEGG: mja:MJ0168 histone A1. (67 aa)    
Predicted Functional Partners:
thrS
TIGRFAM: threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG: mja:MJ1197 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.568
ACX72073.1
PFAM: protein of unknown function DUF106 transmembrane; KEGG: mja:MJ0480 hypothetical protein.
 
     0.520
albA
DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
  
   
 0.507
atpE
H+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.479
ACX72048.1
PFAM: Protein of unknown function DUF63; KEGG: mja:MJ0440 hypothetical protein.
 
     0.447
mtrA
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
  
    0.408
ACX73224.1
PFAM: PilT protein domain protein; KH type 2 domain protein; K Homology, type 1, subgroup; SMART: Nucleotide binding protein PINc; Hedgehog/intein hint domain protein; KH domain protein; KEGG: mja:MJ1533 ATPase.
 
     0.407
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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