STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73518.1DNA binding protein, Tfx family; Putative transcriptional regulator. (137 aa)    
Predicted Functional Partners:
pelA
Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
 
    0.914
ACX73025.1
PFAM: amino acid-binding ACT domain protein; KEGG: mja:MJ1601 hypothetical protein.
  
     0.710
ACX72912.1
PFAM: chromosome segregation and condensation protein ScpA; KEGG: mfe:Mefer_0285 chromosome segregation and condensation protein ScpA.
  
     0.549
ACX72214.1
KEGG: mfe:Mefer_0611 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain protein-like protein.
  
     0.530
ACX73216.1
PFAM: phosphoesterase RecJ domain protein; TrkA-N domain protein; phosphoesterase DHHA1; KEGG: mja:MJ1633 hypothetical protein.
  
     0.489
ACX71922.1
PFAM: Protein of unknown function DUF555; KEGG: mfe:Mefer_0415 protein of unknown function DUF555; Belongs to the UPF0212 family.
  
     0.476
ACX72924.1
Transcriptional regulator, MarR family; PFAM: Helix-turn-helix type 11 domain protein; regulatory protein MarR; SMART: regulatory protein Crp; KEGG: mja:MJ0558 hypothetical protein.
  
     0.472
ACX72330.1
PFAM: UspA domain protein; KEGG: mja:MJ0531 hypothetical protein.
   
    0.460
ACX73194.1
PFAM: Protein of unknown function UPF0058; KEGG: mja:MJ1205 hypothetical protein.
  
     0.460
rpoL
RNA polymerase dimerization; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
     0.447
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.