STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (252 aa)    
Predicted Functional Partners:
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
 
 0.999
rpl18
Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.998
rps4e
PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KOW domain protein; KEGG: mja:MJ0468 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
 
   0.998
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
 
 
 0.998
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.998
rpl2
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
 
 0.998
rpl32e
PFAM: Ribosomal protein L32e; KEGG: mja:MJ0472 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
 
 
 0.997
rps19p
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
 
 
 0.997
rpl30
TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: mja:MJ0476 50S ribosomal protein L30P.
 
 
 0.996
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
 0.996
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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