Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73526.1TIGRFAM: C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: mja:MJ0576 malic acid transport protein. (346 aa)    
Predicted Functional Partners:
ACX73527.1
PFAM: UspA domain protein; KEGG: mja:MJ0577 hypothetical protein.
  
  
 0.818
purC
KEGG: mfe:Mefer_0827 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
       0.624
ACX72473.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: mja:MJ0327 hypothetical protein.
       0.594
purS
Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...]
       0.501
ACX72981.1
KEGG: mja:MJ1242 methyl coenzyme M reductase system, component A2 (AtwA); TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.460
ACX73322.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1662 methyl coenzyme M reductase system, component A2-like.
  
    0.460
ACX72731.1
KEGG: mja:MJ1226 plasma membrane ATPase 1 (aha1); TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein.
  
    0.429
rps19p
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
       0.410
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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