Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73548.1PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1; KEGG: mfe:Mefer_0509 non-specific serine/threonine protein kinase. (302 aa)    
Predicted Functional Partners:
ACX72772.1
PFAM: PilT protein domain protein; SMART: Nucleotide binding protein PINc; KEGG: mja:MJ1474 hypothetical protein.
   
 0.995
ACX72052.1
KEGG: mfe:Mefer_0987 non-specific serine/threonine protein kinase; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1.
  
0.973
rps6e
PFAM: Ribosomal protein S6e; KEGG: mja:MJ1260 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.967
ACX72051.1
KH domain protein; KEGG: mja:MJ0443 putative RNA-processing protein; TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; SMART: KH domain protein.
   
 
 0.962
rps11
Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.960
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
 0.955
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.955
rps15
PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; KEGG: mfe:Mefer_1234 ribosomal S13S15 domain protein.
  
 
 0.952
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.949
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: mja:MJ0980 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.949
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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