STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX73586.1Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ0450 inosine monophosphate dehydrogenase isolog. (173 aa)    
Predicted Functional Partners:
ACX72730.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ1225 hypothetical protein.
 
    0.903
ACX72713.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ1404 hypothetical protein.
 
    0.839
ACX73165.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mfe:Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.741
rps2
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: mfe:Mefer_1409 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.735
ACX72964.1
KEGG: mja:MJ0108 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
 
 
 0.732
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.724
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.719
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.717
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
 
 
 0.716
rpl2
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.714
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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