| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS84342.1 | ACS85802.1 | Dd703_0531 | Dd703_2012 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | 0.976 |
| ACS84342.1 | thiL | Dd703_0531 | Dd703_2896 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.530 |
| ACS84342.1 | tsaC | Dd703_0531 | Dd703_0443 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | SUA5/yciO/yrdC domain protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.460 |
| ACS84342.1 | tsaD | Dd703_0531 | Dd703_3367 | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.900 |
| ACS85801.1 | ACS85802.1 | Dd703_2011 | Dd703_2012 | TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein. | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | 0.656 |
| ACS85801.1 | ACS85803.1 | Dd703_2011 | Dd703_2013 | TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein. | SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase. | 0.481 |
| ACS85802.1 | ACS84342.1 | Dd703_2012 | Dd703_0531 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase. | 0.976 |
| ACS85802.1 | ACS85801.1 | Dd703_2012 | Dd703_2011 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein. | 0.656 |
| ACS85802.1 | ACS85803.1 | Dd703_2012 | Dd703_2013 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase. | 0.649 |
| ACS85802.1 | birA | Dd703_2012 | Dd703_3740 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.910 |
| ACS85802.1 | hisI | Dd703_2012 | Dd703_2234 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; KEGG: eca:ECA2589 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family. | 0.708 |
| ACS85802.1 | tadA | Dd703_2012 | Dd703_2773 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.644 |
| ACS85802.1 | thiL | Dd703_2012 | Dd703_2896 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.591 |
| ACS85802.1 | truA | Dd703_2012 | Dd703_2576 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.499 |
| ACS85802.1 | tsaC | Dd703_2012 | Dd703_0443 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | SUA5/yciO/yrdC domain protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.577 |
| ACS85802.1 | tsaD | Dd703_2012 | Dd703_3367 | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.941 |
| ACS85803.1 | ACS85801.1 | Dd703_2013 | Dd703_2011 | SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase. | TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein. | 0.481 |
| ACS85803.1 | ACS85802.1 | Dd703_2013 | Dd703_2012 | SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase. | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | 0.649 |
| ACS85803.1 | birA | Dd703_2013 | Dd703_3740 | SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase. | Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.444 |
| birA | ACS85802.1 | Dd703_3740 | Dd703_2012 | Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein. | 0.910 |