node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS84156.1 | ACS87592.1 | Dd703_0341 | Dd703_3839 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | KEGG: ypy:YPK_0888 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | 0.908 |
ACS84156.1 | dedD | Dd703_0341 | Dd703_2572 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Sporulation domain protein; Non-essential cell division protein that could be required for efficient cell constriction. | 0.422 |
ACS84156.1 | fadR | Dd703_0341 | Dd703_1983 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | 0.420 |
ACS84156.1 | metJ | Dd703_0341 | Dd703_3792 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.599 |
ACS84156.1 | mutH | Dd703_0341 | Dd703_3019 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.775 |
ACS84156.1 | rraB | Dd703_0341 | Dd703_3565 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.452 |
ACS84156.1 | seqA | Dd703_0341 | Dd703_1122 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.403 |
ACS84156.1 | yihI | Dd703_0341 | Dd703_3965 | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Protein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.456 |
ACS86335.1 | dedD | Dd703_2558 | Dd703_2572 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | Sporulation domain protein; Non-essential cell division protein that could be required for efficient cell constriction. | 0.690 |
ACS86335.1 | fadR | Dd703_2558 | Dd703_1983 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | 0.712 |
ACS86335.1 | metJ | Dd703_2558 | Dd703_3792 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.736 |
ACS86335.1 | mutH | Dd703_2558 | Dd703_3019 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.738 |
ACS86335.1 | rraB | Dd703_2558 | Dd703_3565 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.749 |
ACS86335.1 | seqA | Dd703_2558 | Dd703_1122 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.743 |
ACS86335.1 | yihI | Dd703_2558 | Dd703_3965 | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | Protein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.781 |
ACS87592.1 | ACS84156.1 | Dd703_3839 | Dd703_0341 | KEGG: ypy:YPK_0888 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | 0.908 |
ACS87592.1 | metJ | Dd703_3839 | Dd703_3792 | KEGG: ypy:YPK_0888 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.497 |
ACS87592.1 | mutH | Dd703_3839 | Dd703_3019 | KEGG: ypy:YPK_0888 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.761 |
dedD | ACS84156.1 | Dd703_2572 | Dd703_0341 | Sporulation domain protein; Non-essential cell division protein that could be required for efficient cell constriction. | KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | 0.422 |
dedD | ACS86335.1 | Dd703_2572 | Dd703_2558 | Sporulation domain protein; Non-essential cell division protein that could be required for efficient cell constriction. | PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. | 0.690 |