node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJZ04235.1 | ureA | TW86_22410 | TW86_08645 | Ureidoglycolate hydrolase; Catalyzes the formation of glyoxylate from (S)-ureidoglycolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.913 |
KJZ04235.1 | ureB | TW86_22410 | TW86_08640 | Ureidoglycolate hydrolase; Catalyzes the formation of glyoxylate from (S)-ureidoglycolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.912 |
KJZ04235.1 | ureC | TW86_22410 | TW86_08635 | Ureidoglycolate hydrolase; Catalyzes the formation of glyoxylate from (S)-ureidoglycolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
KJZ06284.1 | ureC | TW86_19570 | TW86_08635 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.649 |
KJZ08148.1 | ureA | TW86_16565 | TW86_08645 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.723 |
KJZ08148.1 | ureB | TW86_16565 | TW86_08640 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.642 |
KJZ08148.1 | ureC | TW86_16565 | TW86_08635 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.724 |
KJZ08148.1 | ureD | TW86_16565 | TW86_08650 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.820 |
KJZ08148.1 | ureE | TW86_16565 | TW86_08630 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.910 |
KJZ08148.1 | ureF | TW86_16565 | TW86_08625 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.979 |
KJZ16232.1 | ureA | TW86_08660 | TW86_08645 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.528 |
KJZ16232.1 | ureB | TW86_08660 | TW86_08640 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.562 |
KJZ16232.1 | ureC | TW86_08660 | TW86_08635 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.567 |
KJZ16232.1 | ureD | TW86_08660 | TW86_08650 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.854 |
KJZ16232.1 | ureE | TW86_08660 | TW86_08630 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.708 |
KJZ16232.1 | ureF | TW86_08660 | TW86_08625 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.709 |
KJZ16232.1 | ureG | TW86_08660 | TW86_08620 | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.503 |
ureA | KJZ04235.1 | TW86_08645 | TW86_22410 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Ureidoglycolate hydrolase; Catalyzes the formation of glyoxylate from (S)-ureidoglycolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
ureA | KJZ08148.1 | TW86_08645 | TW86_16565 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.723 |
ureA | KJZ16232.1 | TW86_08645 | TW86_08660 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urea ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |