STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_001266615_00056Unannotated protein. (178 aa)    
Predicted Functional Partners:
rseA
Unannotated protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]
   
    0.819
GCA_001266615_03872
Unannotated protein.
   
  
 0.714
yeeA
Unannotated protein.
  
     0.581
ndh
Unannotated protein.
       0.534
GCA_001266615_02128
Unannotated protein.
  
  
 0.531
GCA_001266615_03797
Unannotated protein.
  
     0.511
rstB
Unannotated protein.
  
     0.510
ligT
Unannotated protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
  
     0.507
GCA_001266615_04301
Unannotated protein.
  
     0.472
mtfA
Unannotated protein; Involved in the regulation of ptsG expression by binding and inactivating Mlc.
  
     0.470
Your Current Organism:
Kluyvera cryocrescens
NCBI taxonomy Id: 580
Other names: ATCC 33435, CCUG 18767, CDC 2065-78, CIP 82.96, DSM 4588, Escherichia citrophila, JCM 7580, K. cryocrescens, Kluyvera citrophila, LMG 7859, LMG:7859, NBRC 102467, strain 12993
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.