node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001266615_01974 | rseB | GCA_001266615_01974 | GCA_001266615_03767 | Unannotated protein. | Unannotated protein. | 0.725 |
GCA_001266615_01974 | skp | GCA_001266615_01974 | GCA_001266615_03562 | Unannotated protein. | Unannotated protein; Belongs to the skp family. | 0.569 |
GCA_001266615_01974 | smg | GCA_001266615_01974 | GCA_001266615_02692 | Unannotated protein. | Unannotated protein; Belongs to the Smg family. | 0.498 |
GCA_001266615_01974 | zapD | GCA_001266615_01974 | GCA_001266615_00620 | Unannotated protein. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.610 |
coaE | yacG | GCA_001266615_00619 | GCA_001266615_00621 | Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Unannotated protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.802 |
coaE | zapD | GCA_001266615_00619 | GCA_001266615_00620 | Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.991 |
ftsN | metJ | GCA_001266615_01840 | GCA_001266615_01848 | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.603 |
ftsN | rseB | GCA_001266615_01840 | GCA_001266615_03767 | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unannotated protein. | 0.415 |
ftsN | zapD | GCA_001266615_01840 | GCA_001266615_00620 | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.563 |
ftsZ | zapD | GCA_001266615_00626 | GCA_001266615_00620 | Unannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.849 |
metJ | ftsN | GCA_001266615_01848 | GCA_001266615_01840 | Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.603 |
metJ | mlaC | GCA_001266615_01848 | GCA_001266615_01208 | Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Unannotated protein. | 0.468 |
metJ | zapD | GCA_001266615_01848 | GCA_001266615_00620 | Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.577 |
mlaC | metJ | GCA_001266615_01208 | GCA_001266615_01848 | Unannotated protein. | Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.468 |
mlaC | rseB | GCA_001266615_01208 | GCA_001266615_03767 | Unannotated protein. | Unannotated protein. | 0.438 |
mlaC | skp | GCA_001266615_01208 | GCA_001266615_03562 | Unannotated protein. | Unannotated protein; Belongs to the skp family. | 0.510 |
mlaC | zapD | GCA_001266615_01208 | GCA_001266615_00620 | Unannotated protein. | Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.602 |
rseB | GCA_001266615_01974 | GCA_001266615_03767 | GCA_001266615_01974 | Unannotated protein. | Unannotated protein. | 0.725 |
rseB | ftsN | GCA_001266615_03767 | GCA_001266615_01840 | Unannotated protein. | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.415 |
rseB | mlaC | GCA_001266615_03767 | GCA_001266615_01208 | Unannotated protein. | Unannotated protein. | 0.438 |