STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rluA_2Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (219 aa)    
Predicted Functional Partners:
rapA
Unannotated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
   0.810
mnmE
Unannotated protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
 
 0.808
rplM
Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
   0.800
ybeB
Unannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.799
truD
Unannotated protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
    
 
 0.798
rplC
Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
   0.789
rplX
Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
 
 
   0.788
rplU
Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.770
rplQ
Unannotated protein.
   
   0.769
rplO
Unannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   0.767
Your Current Organism:
Kluyvera cryocrescens
NCBI taxonomy Id: 580
Other names: ATCC 33435, CCUG 18767, CDC 2065-78, CIP 82.96, DSM 4588, Escherichia citrophila, JCM 7580, K. cryocrescens, Kluyvera citrophila, LMG 7859, LMG:7859, NBRC 102467, strain 12993
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