node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001266615_03635 | rraA | GCA_001266615_03635 | GCA_001266615_01836 | Unannotated protein. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.747 |
aceA | citE | GCA_001266615_02338 | GCA_001266615_03160 | Unannotated protein. | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | 0.686 |
aceA | rraA | GCA_001266615_02338 | GCA_001266615_01836 | Unannotated protein. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.646 |
bcpA | citE | GCA_001266615_04231 | GCA_001266615_03160 | Unannotated protein. | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | 0.737 |
bcpA | rraA | GCA_001266615_04231 | GCA_001266615_01836 | Unannotated protein. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.696 |
citE | aceA | GCA_001266615_03160 | GCA_001266615_02338 | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | Unannotated protein. | 0.686 |
citE | bcpA | GCA_001266615_03160 | GCA_001266615_04231 | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | Unannotated protein. | 0.737 |
citE | rraA | GCA_001266615_03160 | GCA_001266615_01836 | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.667 |
ftsN | rraA | GCA_001266615_01840 | GCA_001266615_01836 | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.845 |
metH | rraA | GCA_001266615_02342 | GCA_001266615_01836 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.739 |
mhpD_1 | rraA | GCA_001266615_02779 | GCA_001266615_01836 | Unannotated protein. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.639 |
mhpD_2 | rraA | GCA_001266615_02761 | GCA_001266615_01836 | Unannotated protein; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.639 |
rhlB | rraA | GCA_001266615_03689 | GCA_001266615_01836 | Unannotated protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.610 |
rraA | GCA_001266615_03635 | GCA_001266615_01836 | GCA_001266615_03635 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein. | 0.747 |
rraA | aceA | GCA_001266615_01836 | GCA_001266615_02338 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein. | 0.646 |
rraA | bcpA | GCA_001266615_01836 | GCA_001266615_04231 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein. | 0.696 |
rraA | citE | GCA_001266615_01836 | GCA_001266615_03160 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. | 0.667 |
rraA | ftsN | GCA_001266615_01836 | GCA_001266615_01840 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.845 |
rraA | metH | GCA_001266615_01836 | GCA_001266615_02342 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.739 |
rraA | mhpD_1 | GCA_001266615_01836 | GCA_001266615_02779 | Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | Unannotated protein. | 0.639 |