node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
entH | menA | GCA_001266615_02537 | GCA_001266615_01837 | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.690 |
entH | menB | GCA_001266615_02537 | GCA_001266615_02885 | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Unannotated protein; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.838 |
entH | menC | GCA_001266615_02537 | GCA_001266615_02886 | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Unannotated protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.434 |
entH | menD | GCA_001266615_02537 | GCA_001266615_02883 | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Unannotated protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.654 |
entH | ybgC | GCA_001266615_02537 | GCA_001266615_02644 | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Unannotated protein. | 0.560 |
ispA | ispB | GCA_001266615_01484 | GCA_001266615_01213 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Belongs to the FPP/GGPP synthase family. | 0.840 |
ispA | menA | GCA_001266615_01484 | GCA_001266615_01837 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.639 |
ispA | ubiA | GCA_001266615_01484 | GCA_001266615_02367 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.697 |
ispB | ispA | GCA_001266615_01213 | GCA_001266615_01484 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Belongs to the FPP/GGPP synthase family. | 0.840 |
ispB | menA | GCA_001266615_01213 | GCA_001266615_01837 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.857 |
ispB | ubiA | GCA_001266615_01213 | GCA_001266615_02367 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.809 |
ispB | ubiE | GCA_001266615_01213 | GCA_001266615_01560 | Unannotated protein; Belongs to the FPP/GGPP synthase family. | Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.572 |
menA | entH | GCA_001266615_01837 | GCA_001266615_02537 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 0.690 |
menA | ispA | GCA_001266615_01837 | GCA_001266615_01484 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Belongs to the FPP/GGPP synthase family. | 0.639 |
menA | ispB | GCA_001266615_01837 | GCA_001266615_01213 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Belongs to the FPP/GGPP synthase family. | 0.857 |
menA | menB | GCA_001266615_01837 | GCA_001266615_02885 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.820 |
menA | menC | GCA_001266615_01837 | GCA_001266615_02886 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.759 |
menA | menD | GCA_001266615_01837 | GCA_001266615_02883 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.854 |
menA | ubiA | GCA_001266615_01837 | GCA_001266615_02367 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.701 |
menA | ubiE | GCA_001266615_01837 | GCA_001266615_01560 | Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.844 |