STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (700 aa)    
Predicted Functional Partners:
leuS
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 
 0.948
KZD01892.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.936
KZD07014.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.905
KZC98814.1
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.862
KZD10318.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.849
bamD
Transporter; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
       0.842
KZD11927.1
DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.815
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 0.740
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
     
 0.739
KZD12392.1
DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.735
Your Current Organism:
Oceanibaculum pacificum
NCBI taxonomy Id: 580166
Other names: CCTCC AB 209059, LMG 24859, LMG:24859, MCCC 1A02656, O. pacificum, Oceanibaculum pacificum Dong et al. 2010, Rhodospirillaceae bacterium MC2UP-L3, strain LMC2up-L3, strain MC2UP-L3
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