STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_0230KEGG: tte:TTE2512 hypothetical protein; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ. (212 aa)    
Predicted Functional Partners:
Tthe_0370
KEGG: tpd:Teth39_0308 membrane protein-like protein.
  
   
 0.594
Tthe_2159
Membrane protein-like protein protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
  
   
 0.488
Tthe_1876
Phosphomethylpyrimidine kinase; KEGG: ckr:CKR_2589 hypothetical protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
  
 0.478
Tthe_1849
KEGG: tte:TTE2425 hypothetical protein.
  
   
 0.475
Tthe_0229
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.445
Tthe_1450
KEGG: tte:TTE1437 hypothetical protein.
  
     0.442
Tthe_0231
PFAM: Monogalactosyldiacylglycerol synthase; Glycosyltransferase 28 domain; KEGG: cac:CAC2897 UDP-glucuronosyltransferase.
       0.441
ecfT
Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 0.431
Tthe_0232
KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related.
       0.423
Tthe_1038
PFAM: BioY protein; KEGG: tte:TTE0777 uncharacterized ACR.
   
  
 0.413
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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