STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_0644PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: cbe:Cbei_4841 oxidoreductase domain-containing protein. (347 aa)    
Predicted Functional Partners:
Tthe_0642
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: tex:Teth514_1075 xylose isomerase domain-containing protein.
 
  
 0.888
Tthe_0643
PFAM: Xylose isomerase domain protein TIM barrel; AP endonuclease 2 domain protein; KEGG: tpd:Teth39_0592 xylose isomerase domain-containing protein.
 
  
 0.879
Tthe_0641
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: tex:Teth514_1073 oxidoreductase domain-containing protein.
 
    
0.663
Tthe_0645
Beta-mannosidase; KEGG: tpd:Teth39_1928 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 2 sugar binding; Belongs to the glycosyl hydrolase 2 family.
  
  
 0.567
Tthe_2482
PFAM: PfkB domain protein; KEGG: cac:CAC0395 2-keto-3-deoxygluconate kinase (gene KdgK).
 
  
 0.564
pfkB
PfkB domain protein; Catalyzes the ATP-dependent phosphorylation of D-fructose 6- phosphate to fructose 1,6-bisphosphate. Together with the adjacently encoded sucrose 6'-phosphate phosphorylase, may be involved in a new pathway for the degradation of sucrose. Cannot phosphorylate D- fructose; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.537
Tthe_0640
KEGG: tpd:Teth39_0588 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI.
       0.510
Tthe_2393
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: str:Sterm_4045 xylose isomerase domain protein TIM barrel.
 
  
 0.489
Tthe_0839
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: cbh:CLC_3144 AP endonuclease.
 
  
 0.483
lysS
TIGRFAM: lysyl-tRNA synthetase; KEGG: tpd:Teth39_0318 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.457
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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