STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_1034PFAM: NAD synthase; KEGG: csc:Csac_1655 ExsB family protein. (275 aa)    
Predicted Functional Partners:
Tthe_1035
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: tpd:Teth39_1539 NCAIR mutase (PurE)-related protein-like protein.
 
  
 0.988
Tthe_1036
PFAM: protein of unknown function DUF111; KEGG: dth:DICTH_1434 hypothetical protein.
  
 0.981
Tthe_1037
PFAM: protein of unknown function DUF111; KEGG: sat:SYN_00476 hypothetical protein.
 
  
 0.957
Tthe_2432
PFAM: Protein of unknown function DUF2088; KEGG: rci:RCIX1757 hypothetical protein.
 
  
 0.738
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.736
larA
Protein of unknown function DUF2088; Catalyzes the interconversion between the D- and L-isomers of lactate; Belongs to the lactate racemase family.
 
  
 0.732
Tthe_2449
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: tex:Teth514_0192 cobalt transport protein CbiM.
 
    0.591
Tthe_1033
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: tex:Teth514_2221 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.575
Tthe_2451
KEGG: tex:Teth514_0190 cobalt ABC transporter, inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein.
  
    0.554
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.539
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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