STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_1270PFAM: O-methyltransferase family 3; KEGG: tpd:Teth39_1061 O-methyltransferase family protein. (213 aa)    
Predicted Functional Partners:
Tthe_1271
PFAM: peptidase U32; KEGG: tpd:Teth39_1062 peptidase U32.
  
  
 0.903
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.770
Tthe_1272
PFAM: penicillin-binding protein transpeptidase; KEGG: tpd:Teth39_1063 peptidoglycan glycosyltransferase.
       0.639
Tthe_1798
PFAM: peptidase U32; KEGG: tpd:Teth39_0774 peptidase U32.
  
  
 0.584
Tthe_1268
PFAM: protein of unknown function DUF964; KEGG: tpd:Teth39_1058 hypothetical protein; Belongs to the UPF0342 family.
       0.572
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.560
Tthe_1273
RNA polymerase, sigma 28 subunit, SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.555
Tthe_2037
SMART: AAA ATPase; KEGG: tpd:Teth39_0715 phosphoribulokinase/uridine kinase.
  
    0.483
Tthe_1266
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: tpd:Teth39_1056 ferric uptake regulator family protein; Belongs to the Fur family.
       0.434
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.419
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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