STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_1331KEGG: tpd:Teth39_1119 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family. (381 aa)    
Predicted Functional Partners:
Tthe_1345
KEGG: tex:Teth514_1575 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.
 
  
 
0.926
Tthe_1148
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: tte:TTE0925 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.
 
  
 
0.918
Tthe_2367
TIGRFAM: penicillin-binding protein, 1A family; KEGG: tte:TTE0314 membrane carboxypeptidase (penicillin-binding protein); PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.
  
 
 0.916
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.753
Tthe_1772
SMART: PASTA domain containing protein; TIGRFAM: stage V sporulation protein D; KEGG: tte:TTE1651 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein.
 
 
 0.740
Tthe_1334
RNA polymerase, sigma 28 subunit, SigF; KEGG: tex:Teth514_1559 FliA/WhiG family RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-F factor; RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein.
 
     0.699
Tthe_1337
KEGG: tpd:Teth39_1125 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
 
   
 0.696
Tthe_1332
KEGG: tpd:Teth39_1120 anti-sigma-factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
     
 0.641
Tthe_1330
PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: tex:Teth514_1555 tyrosine recombinase XerD; Belongs to the 'phage' integrase family.
       0.636
Tthe_1098
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: syf:Synpcc7942_0647 hypothetical protein.
 
 
 0.621
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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