STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_1347PFAM: glucose-inhibited division protein A; KEGG: tpd:Teth39_1140 glucose-inhibited division protein A. (427 aa)    
Predicted Functional Partners:
Tthe_1346
KEGG: tex:Teth514_1576 hypothetical protein.
 
    0.953
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.701
Tthe_0266
KEGG: tpd:Teth39_0256 hypothetical protein; TIGRFAM: spore cortex biosynthesis protein YabQ; PFAM: Spore cortex biosynthesis protein, YabQ-like.
  
    0.652
Tthe_0057
KEGG: tpd:Teth39_2194 hypothetical protein.
  
     0.651
Tthe_1252
PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: amt:Amet_1237 di-trans-poly-cis-decaprenylcistransferase.
 
    0.591
Tthe_1345
KEGG: tex:Teth514_1575 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.
       0.566
Tthe_1348
KEGG: tpd:Teth39_1141 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family.
  
    0.560
Tthe_1203
KEGG: tpd:Teth39_1362 ubiquitin-associated domain-containing protein; PFAM: ubiquitin-associated- domain-containing protein; SMART: Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote.
  
     0.529
Tthe_1420
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
    0.516
Tthe_1349
PFAM: GCN5-related N-acetyltransferase; KEGG: tpd:Teth39_1142 hypothetical protein.
  
    0.501
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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