Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tthe_1663PFAM: FAD linked oxidase domain protein; KEGG: tte:TTE0224 FAD/FMN-containing dehydrogenase. (470 aa)    
Predicted Functional Partners:
Tthe_1664
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: amt:Amet_3748 electron transfer flavoprotein, alpha subunit-like protein.
 
 
 0.946
Tthe_1665
KEGG: amt:Amet_3749 electron transfer flavoprotein, alpha/beta-subunit-like protein; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SMART: Electron transfer flavoprotein alpha/beta-subunit.
 
 
 0.919
larA
Protein of unknown function DUF2088; Catalyzes the interconversion between the D- and L-isomers of lactate; Belongs to the lactate racemase family.
 
   
 0.855
etfA
Electron transfer flavoprotein alpha subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
 
 
 0.827
Tthe_1666
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.818
etfB
Electron transfer flavoprotein alpha/beta-subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
 
 
 0.812
Tthe_1667
KEGG: amt:Amet_0818 GntR domain-containing protein; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; GntR domain protein.
 
  
 0.613
Tthe_1119
KEGG: tpd:Teth39_1457 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Soluble ligand binding domain; Sucraseferredoxin family protein.
   
 0.543
Tthe_2646
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: tex:Teth514_0627 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.463
Tthe_0587
PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: tpd:Teth39_0537 FAD dependent oxidoreductase.
     
 0.456
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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