node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tthe_0771 | Tthe_1550 | Tthe_0771 | Tthe_1550 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.914 |
Tthe_0771 | Tthe_1943 | Tthe_0771 | Tthe_1943 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | 0.900 |
Tthe_0771 | Tthe_2014 | Tthe_0771 | Tthe_2014 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tte:TTE1757 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. | 0.900 |
Tthe_0771 | folE | Tthe_0771 | Tthe_0381 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | TIGRFAM: GTP cyclohydrolase I; KEGG: tpd:Teth39_0319 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.815 |
Tthe_0771 | ndk | Tthe_0771 | Tthe_1025 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.909 |
Tthe_0771 | polA | Tthe_0771 | Tthe_1101 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.514 |
Tthe_0771 | ribBA | Tthe_0771 | Tthe_0022 | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.800 |
Tthe_1550 | Tthe_0771 | Tthe_1550 | Tthe_0771 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | 0.914 |
Tthe_1550 | Tthe_1943 | Tthe_1550 | Tthe_1943 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | 0.900 |
Tthe_1550 | folE | Tthe_1550 | Tthe_0381 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | TIGRFAM: GTP cyclohydrolase I; KEGG: tpd:Teth39_0319 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.800 |
Tthe_1550 | ndk | Tthe_1550 | Tthe_1025 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
Tthe_1550 | polA | Tthe_1550 | Tthe_1101 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.598 |
Tthe_1550 | ribBA | Tthe_1550 | Tthe_0022 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.855 |
Tthe_1942 | Tthe_1943 | Tthe_1942 | Tthe_1943 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: tte:TTE1849 pyruvate-formate lyase-activating enzyme; SMART: Elongator protein 3/MiaB/NifB. | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | 0.996 |
Tthe_1943 | Tthe_0771 | Tthe_1943 | Tthe_0771 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. | 0.900 |
Tthe_1943 | Tthe_1550 | Tthe_1943 | Tthe_1550 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
Tthe_1943 | Tthe_1942 | Tthe_1943 | Tthe_1942 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: tte:TTE1849 pyruvate-formate lyase-activating enzyme; SMART: Elongator protein 3/MiaB/NifB. | 0.996 |
Tthe_1943 | Tthe_2014 | Tthe_1943 | Tthe_2014 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tte:TTE1757 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. | 0.900 |
Tthe_1943 | dut | Tthe_1943 | Tthe_1400 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.941 |
Tthe_1943 | folE | Tthe_1943 | Tthe_0381 | KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | TIGRFAM: GTP cyclohydrolase I; KEGG: tpd:Teth39_0319 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.800 |