Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lgt-2Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (258 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.739
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.653
Tthe_2001
KEGG: tpd:Teth39_0753 putative GAF sensor protein; PFAM: GAF domain protein; SMART: GAF domain protein.
       0.604
Tthe_0483
PFAM: UspA domain protein; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein.
  
     0.537
Tthe_2003
Glycoside hydrolase family 18; KEGG: tte:TTE1747 hypothetical protein; PFAM: glycoside hydrolase family 18; SMART: chitinase II.
       0.510
Tthe_2187
Glycosyl transferase family 2; KEGG: tte:TTE0501 cell wall biosynthesis glycosyltransferase; PFAM: glycosyl transferase family 2; Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; glycosyl transferase group 1; SMART: Tetratricopeptide repeat.
 
    0.504
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
  
  
 0.503
Tthe_0328
PFAM: NAD/NADP octopine/nopaline dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: tex:Teth514_2108 NAD/NADP octopine/nopaline dehydrogenase.
 
    0.500
Tthe_2754
Membrane protein insertase, YidC/Oxa1 family; KEGG: tpd:Teth39_2292 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein.
  
  
 0.479
Tthe_0342
KEGG: tte:TTE2401 hypothetical protein.
  
     0.469
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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