Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_2011PFAM: protein of unknown function DUF633; KEGG: tex:Teth514_1316 hypothetical protein. (246 aa)    
Predicted Functional Partners:
Tthe_2010
PFAM: protein of unknown function DUF34; KEGG: tpd:Teth39_0741 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
  
 0.985
Tthe_1263
PFAM: protein of unknown function DUF965; KEGG: tpd:Teth39_1053 hypothetical protein; Belongs to the UPF0297 family.
  
     0.733
Tthe_1475
Putative helix-turn-helix protein YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.611
Tthe_2730
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.605
Tthe_1558
KEGG: tex:Teth514_1460 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.597
Tthe_1535
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: tpd:Teth39_1330 fibronectin-binding A domain-containing protein.
 
     0.589
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.553
Tthe_2736
PFAM: protein of unknown function DUF951; KEGG: tpd:Teth39_2276 hypothetical protein.
  
     0.526
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.517
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
     0.516
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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