STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tthe_2205PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; KEGG: sth:STH926 2-cys peroxiredoxin. (166 aa)    
Predicted Functional Partners:
Tthe_0389
KEGG: tpd:Teth39_0328 hypothetical protein.
  
 0.947
Tthe_0477
KEGG: tpd:Teth39_0445 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.849
Tthe_2204
PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: tte:TTE0487 rubrerythrin.
  
  
 0.806
Tthe_0588
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tte:TTE2000 uncharacterized NAD(FAD)-dependent dehydrogenase.
  
 
 0.792
Tthe_0249
KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rhodanese domain protein; DsrE family protein; SirA family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family.
  
  
 0.775
Tthe_1088
PFAM: Manganese/iron superoxide dismutase-like; KEGG: tte:TTE0857 superoxide dismutase.
 
  
 0.662
Tthe_1266
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: tpd:Teth39_1056 ferric uptake regulator family protein; Belongs to the Fur family.
 
  
 0.578
Tthe_2026
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: tpd:Teth39_0726 ferric uptake regulator family protein; Belongs to the Fur family.
  
  
 0.568
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.553
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.526
Your Current Organism:
Thermoanaerobacterium thermosaccharolyticum
NCBI taxonomy Id: 580327
Other names: T. thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum DSM 571, Thermoanaerobacterium thermosaccharolyticum str. DSM 571, Thermoanaerobacterium thermosaccharolyticum strain DSM 571
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