Slit_0002 protein (Sideroxydans lithotrophicus)

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Slit_0002

DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)

Predicted Functional Partners:

Slit_1536

0.997

Slit_2567

0.993

dnaA

0.991

Slit_2849

0.991

dnaX

0.990

polA

0.988

dnaQ

0.987

Slit_2411

0.972

gyrB

0.968

Slit_2503

0.963

Your Current Organism:

Sideroxydans lithotrophicus

NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Slit_0002	Slit_1536	Slit_0002	Slit_1536	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	0.997
Slit_0002	Slit_2411	Slit_0002	Slit_2411	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: DNA polymerase III chi subunit HolC; KEGG: nmu:Nmul_A0745 DNA polymerase III chi subunit, HolC.	0.972
Slit_0002	Slit_2503	Slit_0002	Slit_2503	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: tbd:Tbd_0089 exonuclease; SMART: Exonuclease.	0.963
Slit_0002	Slit_2567	Slit_0002	Slit_2567	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein; KEGG: mei:Msip34_1749 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein.	0.993
Slit_0002	Slit_2849	Slit_0002	Slit_2849	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, delta subunit; KEGG: har:HEAR2663 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	0.991
Slit_0002	dnaA	Slit_0002	Slit_0001	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.991
Slit_0002	dnaQ	Slit_0002	Slit_1512	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.987
Slit_0002	dnaX	Slit_0002	Slit_1265	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.990
Slit_0002	gyrB	Slit_0002	Slit_0003	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.968
Slit_0002	polA	Slit_0002	Slit_2833	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.988
Slit_1536	Slit_0002	Slit_1536	Slit_0002	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.997
Slit_1536	Slit_2411	Slit_1536	Slit_2411	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	PFAM: DNA polymerase III chi subunit HolC; KEGG: nmu:Nmul_A0745 DNA polymerase III chi subunit, HolC.	0.990
Slit_1536	Slit_2503	Slit_1536	Slit_2503	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: tbd:Tbd_0089 exonuclease; SMART: Exonuclease.	0.926
Slit_1536	Slit_2567	Slit_1536	Slit_2567	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein; KEGG: mei:Msip34_1749 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein.	0.990
Slit_1536	Slit_2849	Slit_1536	Slit_2849	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	TIGRFAM: DNA polymerase III, delta subunit; KEGG: har:HEAR2663 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	0.994
Slit_1536	dnaQ	Slit_1536	Slit_1512	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.939
Slit_1536	dnaX	Slit_1536	Slit_1265	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.993
Slit_1536	polA	Slit_1536	Slit_2833	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.906
Slit_2411	Slit_0002	Slit_2411	Slit_0002	PFAM: DNA polymerase III chi subunit HolC; KEGG: nmu:Nmul_A0745 DNA polymerase III chi subunit, HolC.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.972
Slit_2411	Slit_1536	Slit_2411	Slit_1536	PFAM: DNA polymerase III chi subunit HolC; KEGG: nmu:Nmul_A0745 DNA polymerase III chi subunit, HolC.	KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.	0.990

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