STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0013Two component transcriptional regulator, Fis family; KEGG: reh:H16_A3694 response regulator; PFAM: response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver. (213 aa)    
Predicted Functional Partners:
Slit_0012
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: nmu:Nmul_A0390 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS domain containing protein.
 
 0.995
Slit_0011
Conserved hypothetical protein; Manually curated; KEGG: app:CAP2UW1_0048 hypothetical protein.
 
     0.928
Slit_1153
KEGG: tmz:Tmz1t_2020 sigma54 specific transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein.
 
     0.913
Slit_0801
KEGG: tgr:Tgr7_0682 sigma54 specific transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein.
 
     0.912
Slit_0856
Transcriptional regulator, NifA, Fis Family; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; KEGG: azo:azo0519 nif-specific regulatory protein; SMART: GAF domain protein; AAA ATPase.
 
 
   0.911
lpxC
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
      0.899
Slit_0010
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.813
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.810
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.796
Slit_1013
KEGG: rpi:Rpic_0575 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.
  
 
   0.710
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.