Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0034AmpG-related permease; KEGG: dar:Daro_0128 major facilitator transporter; TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1. (419 aa)    
Predicted Functional Partners:
Slit_0035
KEGG: nmu:Nmul_A0222 methionine biosynthesis MetW; TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein.
       0.793
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
       0.793
Slit_2632
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; KEGG: neu:NE2182 N-acetyl-anhydromuranmyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2.
 
   
 0.513
Slit_0046
PFAM: aminoglycoside phosphotransferase; KEGG: tmz:Tmz1t_1453 aminoglycoside phosphotransferase.
 
   
 0.502
Slit_0033
Conserved hypothetical protein; Manually curated; KEGG: bac:BamMC406_5360 hypothetical protein.
       0.459
nagZ
Glycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
   
 0.445
Slit_0037
KEGG: mmb:Mmol_2176 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.442
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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