Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0049KEGG: nmu:Nmul_A0130 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding. (386 aa)    
Predicted Functional Partners:
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.979
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
  
 0.920
Slit_0362
PFAM: Methyltransferase type 11; KEGG: tbd:Tbd_2758 demethylmenaquinone methyltransferase.
     
 0.901
Slit_0582
PFAM: peptidase U32; KEGG: dar:Daro_0108 peptidase U32.
     
 0.901
Slit_0581
PFAM: Sterol-binding domain protein; KEGG: app:CAP2UW1_0991 hypothetical protein.
     
 0.900
Slit_0583
PFAM: peptidase U32; KEGG: app:CAP2UW1_0989 peptidase U32.
     
  0.900
Slit_0048
PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: mei:Msip34_0582 peptidase M24.
  
  
 0.836
Slit_0047
PFAM: Nucleotidyl transferase; KEGG: tmz:Tmz1t_1452 nucleotidyl transferase.
       0.809
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
       0.773
coq7
Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
  
 0.742
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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