STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0061KEGG: azo:azo3758 hypothetical protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein. (151 aa)    
Predicted Functional Partners:
Slit_0060
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.520
Slit_0058
KEGG: chl:Chy400_0933 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type.
       0.476
Slit_0059
KEGG: dma:DMR_29960 hypothetical protein.
       0.476
Slit_0423
KEGG: dar:Daro_1048 coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; manually curated; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
   
    0.442
Slit_0057
KEGG: mfa:Mfla_0379 peptidylprolyl isomerase; PFAM: peptidylprolyl isomerase FKBP-type.
       0.413
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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