Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0062TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: neu:NE0193 Mg(2+) chelatase family protein; SMART: AAA ATPase. (496 aa)    
Predicted Functional Partners:
Slit_0006
KEGG: nmu:Nmul_A0395 DNA processing protein DprA, putative; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.
 
 0.913
Slit_2590
PFAM: phosphoribosyltransferase; KEGG: nmu:Nmul_A1128 phosphoribosyltransferase.
 
  
 0.862
Slit_0063
PFAM: protein of unknown function DUF526; KEGG: mms:mma_0167 hypothetical protein.
       0.813
Slit_1396
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: nmu:Nmul_A2506 DNA internalization-related competence protein ComEC/Rec2; SMART: beta-lactamase domain protein.
 
  
 0.682
Slit_2964
PFAM: protein of unknown function UPF0102; KEGG: cti:RALTA_A3032 conserved hypothetical protein, UPF0102; Belongs to the UPF0102 family.
 
  
 0.675
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.547
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
     0.527
Slit_0064
PFAM: conserved hypothetical protein; KEGG: dar:Daro_0052 hypothetical protein.
       0.524
Slit_0065
PFAM: nitrogen regulatory protein P-II; KEGG: dar:Daro_0053 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
       0.413
Slit_0066
KEGG: dar:Daro_0054 ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter.
       0.404
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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