Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0093PFAM: Creatininase; KEGG: dar:Daro_0078 creatininase. (256 aa)    
Predicted Functional Partners:
Slit_0091
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dar:Daro_0080 binding-protein dependent transport system inner membrane protein.
 
     0.920
Slit_0090
PFAM: NMT1/THI5 like domain protein; KEGG: dar:Daro_0081 ABC transport system substrate-binding protein.
 
     0.909
Slit_0092
ABC transporter related protein; KEGG: bxe:Bxe_B1387 nitrate/sulfonate/bicarbonate ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
     0.890
Slit_0094
Glutamine synthetase, type III; KEGG: dar:Daro_0077 L-glutamine synthetase; TIGRFAM: glutamine synthetase, type III; PFAM: glutamine synthetase catalytic region.
 
   
 0.878
Slit_0095
Transcriptional regulator NikR, CopG family; Transcriptional regulator.
 
     0.724
Slit_0080
TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; KEGG: nmu:Nmul_A0943 allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; biotin carboxylase domain protein; Allophanate hydrolase subunit 1.
 
    0.413
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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