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hemE protein (Sideroxydans lithotrophicus) - STRING interaction network
"hemE" - Uroporphyrinogen decarboxylase in Sideroxydans lithotrophicus
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (314 aa)
 
  0.992
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (304 aa)
 
 
  0.991
Slit_0115
Glutamate synthase (ferredoxin) (1565 aa)
   
   
  0.982
Slit_0423
Oxygen-independent coproporphyrinogen III oxidase (467 aa)
 
 
  0.974
Slit_0405
Oxygen-independent coproporphyrinogen III oxidase (399 aa)
 
 
  0.967
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (458 aa)
       
  0.950
Slit_0268
Uroporphyrinogen III synthase HEM4 (258 aa)
   
 
  0.947
Slit_0037
Porphobilinogen synthase (333 aa)
 
 
  0.947
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX (362 aa)
 
   
  0.918
hemL
Glutamate-1-semialdehyde-2,1-aminomutase (427 aa)
 
   
  0.911
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus, S. lithotrophicus ES-1, Siderooxidans, Siderooxidans lithoautotrophicus, Sideroxydans, Sideroxydans lithotrophicus, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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