Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0125PFAM: aldo/keto reductase; KEGG: rpf:Rpic12D_4663 aldo/keto reductase. (344 aa)    
Predicted Functional Partners:
Slit_1540
KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
   
  0.583
Slit_1343
PFAM: aldo/keto reductase; KEGG: ypb:YPTS_1101 aldo/keto reductase.
 
 
0.573
argS
TIGRFAM: arginyl-tRNA synthetase; KEGG: mei:Msip34_2807 arginyl-tRNA synthetase.
       0.518
Slit_0129
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A2453 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.499
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
  
 0.477
Slit_0124
KEGG: pna:Pnap_2775 putative transmembrane protein.
       0.470
Slit_0127
PFAM: Sporulation domain protein; KEGG: cvi:CV_3999 hypothetical protein.
       0.470
Slit_0123
KEGG: rpf:Rpic12D_5285 phosphoesterase PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related.
       0.461
Slit_0128
PFAM: DSBA oxidoreductase; KEGG: nmu:Nmul_A2454 DsbA oxidoreductase.
       0.414
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.