STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0128PFAM: DSBA oxidoreductase; KEGG: nmu:Nmul_A2454 DsbA oxidoreductase. (206 aa)    
Predicted Functional Partners:
dsbB
Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
 
 0.922
Slit_0129
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A2453 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.789
Slit_0127
PFAM: Sporulation domain protein; KEGG: cvi:CV_3999 hypothetical protein.
 
     0.734
argS
TIGRFAM: arginyl-tRNA synthetase; KEGG: mei:Msip34_2807 arginyl-tRNA synthetase.
       0.640
dsbD
Cytochrome c biogenesis protein transmembrane region; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.607
bamE
SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.555
lptA
Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
 
   
 0.514
Slit_0648
PFAM: Stringent starvation protein B; KEGG: tbd:Tbd_1829 ClpXP protease specificity-enhancing factor.
  
     0.506
Slit_2768
PFAM: cytochrome c biogenesis protein transmembrane region; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_6268 cytochrome c biogenesis protein, transmembrane region.
  
 
 0.490
apaH
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
  
     0.482
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: medium (74%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.