Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0129PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A2453 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (262 aa)    
Predicted Functional Partners:
Slit_0128
PFAM: DSBA oxidoreductase; KEGG: nmu:Nmul_A2454 DsbA oxidoreductase.
       0.789
Slit_0127
PFAM: Sporulation domain protein; KEGG: cvi:CV_3999 hypothetical protein.
       0.720
argS
TIGRFAM: arginyl-tRNA synthetase; KEGG: mei:Msip34_2807 arginyl-tRNA synthetase.
       0.665
Slit_0125
PFAM: aldo/keto reductase; KEGG: rpf:Rpic12D_4663 aldo/keto reductase.
 
  
 0.499
Slit_0132
PFAM: cytochrome c1; KEGG: pla:Plav_2244 cytochrome c1.
   
   0.460
Slit_0131
Cytochrome b/b6 domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
     
 0.459
Slit_0130
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
       0.458
Slit_0737
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: dar:Daro_0627 nucleoid occlusion protein.
  
   
 0.443
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
  
     0.431
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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