STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
Slit_0150Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: oca:OCAR_7493 putative sensor histidine kinase. (689 aa)    
Predicted Functional Partners:
Slit_0151
Two component transcriptional regulator, LuxR family; KEGG: mpt:Mpe_A3237 response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
   0.954
Slit_2215
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: rmr:Rmar_2228 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein.
  
 
   0.700
Slit_2581
Two component transcriptional regulator, LuxR family; KEGG: mag:amb3889 response regulator; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver.
  
   0.679
Slit_2214
KEGG: pol:Bpro_0709 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
  
   0.675
Slit_2168
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mag:amb3563 C4-dicarboxylate transport sensor protein DctB; SMART: ATP-binding region ATPase domain protein.
  
     0.667
Slit_0622
KEGG: har:HEAR1863 LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
  
   0.648
Slit_2500
Two component transcriptional regulator, LuxR family; KEGG: rsk:RSKD131_3304 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
  
   0.643
Slit_1592
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; KEGG: dze:Dd1591_1894 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
 
   0.641
Slit_1727
KEGG: tbd:Tbd_2464 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
  
   0.623
Slit_0623
PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; manually curated; KEGG: mms:mma_1453 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein.
  
     0.621
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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